RYZUP^® Support Services

With RYZUP Support Services, you have support during your entire LUMRYZ^® treatment journey

ryzup support services

RYZUP Nurse Care Navigators (NCNs) are just a phone call away

Your NCNs are dedicated to assisting you with starting LUMRYZ and will be with you throughout your treatment. They can answer questions about insurance coverage and financial assistance as you start LUMRYZ or if your situation changes.*

Once you and your healthcare provider decide to start you on LUMRYZ, it’s helpful to have a clear picture of what comes next:

Enrollment:

At your appointment, your healthcare provider submits forms to enroll you in:

The LUMRYZ REMS
RYZUP Support Services

Insurance and approval:

RYZUP Support Services works directly with your healthcare provider to determine your insurance plan’s coverage requirements.  

You’ll receive a call directly from your RYZUP NCN to update you on the status and answer questions about LUMRYZ that you may have.

Specialty pharmacy shipping:

LUMRYZ is available from a select group of specialty pharmacies. A specialty pharmacy provides medicines that aren't typically available at a local retail pharmacy.  

A pharmacist will call you to discuss your prescription and coordinate the shipment. LUMRYZ will be shipped directly to you once your coverage is confirmed. 

Want more details? Download the Starting and
Taking LUMRYZ Timeline

Oxybate Questionnaire

Download the timeline

At every step of your treatment, dedicated NCNs will be there for you

Your NCN team will support your access to LUMRYZ and are available to answer product questions throughout your treatment*:

Follow up to capture any missing information or signatures to help complete your enrollment
Answer questions you have about LUMRYZ (including LUMRYZ savings and access programs)
Provide educational information and resources
Work with your healthcare and insurance providers to help determine coverage and your out-of-pocket costs

*NCNs do not provide medical advice or manage symptoms. You should discuss medical questions or concerns with your healthcare provider.

Once you start LUMRYZ, your specialty pharmacy is also a resource for you, and has 24/7 pharmacist support.

Find out more about starting LUMRYZ

Connect with a real person taking LUMRYZ

Register for the LUMRYZ  Mentor Program

More questions about LUMRYZ?

Explore the FAQs

REMS, Risk Evaluation and Mitigation Strategy.

INDICATIONS

LUMRYZ (sodium oxybate) for extended-release oral suspension is a prescription medicine used to treat the following symptoms in patients 7 years of age and older with narcolepsy:

sudden onset of weak or paralyzed muscles (cataplexy)
excessive daytime sleepiness (EDS)

IMPORTANT SAFETY INFORMATION

WARNING: Taking LUMRYZ^® (sodium oxybate) with other central nervous system (CNS) depressants such as medicines used to make you fall asleep, including opioid analgesics, benzodiazepines, sedating antidepressants, antipsychotics, sedating anti-epileptic medicines, general anesthetics, muscle relaxants, alcohol, or street drugs, may cause serious medical problems, including trouble breathing (respiratory depression), low blood pressure (hypotension), changes in alertness (drowsiness), fainting (syncope), and death.

The active ingredient of LUMRYZ (sodium oxybate) is a form of gamma hydroxybutyrate (GHB), a controlled substance. Abuse or misuse of illegal GHB alone or with other CNS depressants (drugs that cause changes in alertness or consciousness) have caused serious side effects. These effects include seizures, trouble breathing (respiratory depression), changes in alertness (drowsiness), coma, and death. Call your doctor right away if you have any of these serious side effects.

Because of these risks, LUMRYZ is available only by prescription and filled through certified pharmacies in the LUMRYZ REMS program. You must be enrolled in the LUMRYZ REMS to receive LUMRYZ. Further information is available at www.LUMRYZREMS.com or by calling 1-877-453-1029.

Do not take LUMRYZ if you take or your child takes other sleep medicines or sedatives (medicines that cause sleepiness), drink alcohol, or have a rare problem called succinic semialdehyde dehydrogenase deficiency.

Keep LUMRYZ in a safe place to prevent abuse and misuse. Selling or giving away LUMRYZ may harm others and is against the law. Tell your doctor if you or your child have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

Anyone who takes LUMRYZ should not do anything that requires them to be fully awake or is dangerous, including driving a car, using heavy machinery, or flying an airplane, for at least six (6) hours after taking LUMRYZ. Those activities should not be done until you know how LUMRYZ affects you.

Falling asleep quickly, including while standing or while getting up from the bed, has led to falls with injuries that have required some people to be hospitalized.

LUMRYZ can cause serious side effects, including the following:

Breathing problems, including slower breathing, trouble breathing, and/or short periods of not breathing while sleeping (eg, sleep apnea). People who already have breathing or lung problems have a higher chance of having breathing problems when they take LUMRYZ.
Mental health problems, including confusion, seeing or hearing things that are not real (hallucinations), unusual or disturbing thoughts (abnormal thinking), feeling anxious or upset, depression, thoughts of killing yourself or trying to kill yourself, increased tiredness, feelings of guilt or worthlessness, and difficulty concentrating. Tell your doctor if you or your child have or had depression or have tried to harm yourself. Call your doctor right away if you or your child have symptoms of mental health problems or a change in weight or appetite.
Sleepwalking. Sleepwalking can cause injuries. Call your doctor if you or your child start sleepwalking.

Tell your doctor if you or your child are on a salt-restricted diet or have high blood pressure, heart failure, or kidney problems. LUMRYZ contains a lot of sodium (salt) and may not be right for you.

The most common side effects of LUMRYZ in adults include nausea, dizziness, bedwetting, headache, and vomiting. Your side effects may increase when you take higher doses of LUMRYZ. The most common side effects in children include nausea, bedwetting, vomiting, headache, decreased weight, decreased appetite, dizziness, and sleepwalking.

LUMRYZ can cause physical dependence and craving for the medicine when it is not taken as directed. These are not all the possible side effects of LUMRYZ.

For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information, including BOXED Warning, and Medication Guide.