Ready to switch or start on once-at-bedtime LUMRYZ?
For adults: Once you and your healthcare provider have decided that LUMRYZ is right for you, your healthcare provider will work with you to consider the best way to start treatment*
Switching to LUMRYZ
If you ARE currently taking a sodium oxybate:
Your healthcare provider can switch you to LUMRYZ at the closest dose—equal to the amount of medicine you’re taking now.
Starting with LUMRYZ
If you ARE NOT currently taking a sodium oxybate:
Your healthcare provider will start you on the lowest dose of LUMRYZ and increase your dose gradually over time until you reach the dose that’s right for you.
*For pediatric dosing, please see the full Prescribing Information.

It may take time before noticing a difference with LUMRYZ
In the clinical trial, some participants saw improvement in their symptoms by week 3 on a 6-g dose, while others saw improvement at week 13 after increasing to the 9-g dose.†
†The LUMRYZ double-blind, placebo-controlled clinical trial included participants with narcolepsy treated with LUMRYZ (n=107). The results measured at week 3 (n=88), week 8 (n=77), and week 13 (n=69) showed daytime symptom improvement of participants on the 6-g, 7.5-g, and 9-g doses of LUMRYZ, respectively. Individual results may vary.
Premeasured packets contain your prescribed dose each time
Each dosage strength comes in a different-color packet.

See how LUMRYZ helped treat the daytime symptoms of narcolepsy for these individuals.

"I like the dosing packets for LUMRYZ because I don’t have to measure it myself. It allows me to just focus on mixing the medicine and not have to guess or stress that I got the right amount."
– Tyler F., living with narcolepsy and treating with LUMRYZ Tyler was compensated by Avadel Pharmaceuticals for his time. Individual results may vary.
How does LUMRYZ fit into your bedtime routine?
LUMRYZ should be taken at least 2 hours after eating to help the medicine absorb into the bloodstream and should be the last thing you do before going to bed
Each premeasured packet contains your full prescribed dose:

at your bedside by pouring water, then adding 1 premeasured packet into the provided mixing cup. Do not use hot water.

for at least 60 seconds (1 minute).

your medicine and lie in bed as you may fall asleep quickly.‡
Make sure to take all the medicine in the mixing cup. After, add more water to the mixing cup and shake well again for 10 seconds, then take what remains of the mixture.

Because of this extended-release formulation, LUMRYZ does not fully dissolve in water and will have a gritty texture even after being shaken thoroughly in the mixing cup.
‡Avoid getting out of your bed after taking LUMRYZ. Some people fall asleep within 5 minutes of taking LUMRYZ and most will fall asleep within 15 minutes. The time it takes you to fall asleep might be different from night to night.
These instructions are not complete. Please see Instructions for Use for complete administration directions.
Watch this step-by-step guide on how to take LUMRYZ:
Once-at-bedtime LUMRYZ offers you:
To learn more about LUMRYZ, download a copy of the LUMRYZ Digital Brochure.
Learn about the process of getting started on LUMRYZ with RYZUP Support Services.