Once-at-bedtime LUMRYZ is designed differently

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LUMRYZ is the first and only FDA-approved treatment to help improve symptoms of cataplexy or excessive daytime sleepiness (EDS) with a once-at-bedtime dose

Other oxybate options require waking up in the middle of the night to take a second dose.

LUMRYZ contains a unique blend of granules that work in 2 ways:

Image of person pouring medicine into mixing cup with water inside enzyme graphic Each dosage strength comes in a different-color packet.
  • Immediate-release

    granules start working as you fall asleep

  • Controlled-release

    granules start working later in place of waking for a second dose

The active ingredient in LUMRYZ is sodium oxybate.

Sodium oxybate is strongly recommended by the American Academy of Sleep Medicine (AASM) to treat narcolepsy. This is based on evidence that it reduces cataplexy and EDS.

Download the LUMRYZ Digital Brochure for an offline guide.


How does LUMRYZ fit into your bedtime routine?

LUMRYZ should be taken at least 2 hours after eating and should be the last thing you do before going to bed

Each premeasured packet contains your full prescribed dose:

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at your bedside by pouring water, then adding 1 premeasured packet into the provided mixing cup. Do not use hot water.

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for at least 60 seconds (1 minute).

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your medicine and lie in bed as you may fall asleep quickly.*

The mixture will taste salty and appear slightly milky with some granules that stick together even when fully mixed.

Watch this step-by-step guide on how to take LUMRYZ:

link to step-by-step guide video

LUMRYZ offers you:

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The potential for less interrupted sleep

No second dose waiting on your nightstand to take in the middle of the night.

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Premeasured packets

Contain the prescribed dose each time.

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Discreet and convenient travel

Pack the number of dose packets you will need for your trip.

See how LUMRYZ helped treat the daytime symptoms of narcolepsy for these individuals.
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How to Get LUMRYZ

Once you and your doctor have decided that LUMRYZ is right for you, your doctor’s office will help you enroll in RYZUP Support Services and the LUMRYZ Risk Evaluation and Mitigation Strategy (REMS).

Learn more about the process of getting started on LUMRYZ with RYZUP Support Services

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Explore how LUMRYZ may help treat your daytime symptoms of narcolepsy

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